Conceptual Architecture

A systems view of the proposed Redoxoflavin Regulatory Protein (RFR).

RFR architecture diagram

Figure A. Sensor → Controller → Effector with negative feedback (set-point restoration).

Modules

Sensor: flavin-binding domain sensitive to redox state and/or electron pressure.
Controller: hysteresis (distinct ON/OFF thresholds) plus an integrator to respond to sustained drift.
Effector: activation of endogenous programs rather than direct chemical forcing.
Shutdown: degron/kill-switch logic to disengage once homeostasis returns.

Design constraints

Closed-loop control (avoid constant activation).
Prevent oscillation and overcorrection.
Prioritize safety and reversibility in early prototypes.